Obesity

Obesity is a condition in which excessive fat accumulated in adipose tissue impairs health. Being Obese, weight-history period was taken prior to baseline (start of the 12-year follow-up), which was considered an adequate period of time to obtain minimally biased estimates of BMI. Scientifically, According to the world health organization WHO (2006), a person is said to be normal weight if he or she has a Body mass index between 18.50 and 24.99. A person with a Body mass index of 25 or more is considered overweight while anyone with BMI of 30 or more is considered obese. Obesity leads to major health issues and reasons to death worldwide.

•    Prevalence 
•    Awareness
 

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Obesity Causes

There are genetic, interactive and hormonal effects on weight, Obesity occurs when you intake more calories than you burn through exercise and ordinary day by day activities. Your body deposits these excess calories as fat. Obesity can sometimes be outlined to a medical cause, such as Prader-Willi disorder, Cushing's syndrome, and different diseases and conditions. The excessive fat increases the risk of numerous health problems. The condition is caused when the body is consuming more calories than it utilizes. Improper diet, lack of physical activities, unhealthy lifestyle, environmental and behavioral factors is some of the few causes for obesity.

•    Food addiction
•    Insulin resistance
•    Sedentary life
•    Gut bacteria
•    PCOS in women
 

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Genetics of obesity

Recent studies have verified and identified variants in several genes might contribute to body fat distribution and eventually weight gain. Occurance of Inheritable forms of obesity is evidence that fatness is caused by genetic mutations; seventy eight cases worldwide are attributed to mutations of seven distinct genes. Candidate gene and genome-wide association examines have led to the discovery of nine locus concerned in Mendelian forms of obesity and 58 locus put-up to polygenic obesity. These locus justify a small fraction of the heritability for obesity and many genes remain to be discovered.

•    Prader–Willi syndrome
•    Bardet–Biedl syndrome
•    Cohen syndrome
•    MOMO syndrome
•    Alstrom syndrome
•    Carpenter syndrome
•    Rubinstein-Taybi syndrome
 

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Childhood Obesity

Childhood obesity has rapidly doubled in children within 30 years. This is the condition where excessive body fat has a negative impact on a child’s health. Rising prevalence of childhood obesity and its many adverse health effects is strongly associated with hazard factors for cardiovascular ailment, type 2 diabetes, orthopedics, intellectual problems, and underachievement in faculty and lower shallowness. Children with obesity are at higher threat of getting distinctive persistent fitness situations and illnesses that effects physical health.

•    Depression
•    High cholesterol
•    Eating and physical activity behaviors
•    Health education
•    Sports programs
 

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Obesity in women

Obesity in women is mainly connected with the risks embody cardiovascular ailment, high blood pressure, reproductive cycle with a restriction in fertility with an increased risk of polycystic ovarian syndrome (PCOS) and irregular or no ovulation. Overweight women suffer from PCOS shows insulin resistance which prone to developing diabetes. These health issues causes less success rate of fertility and more complicated. 

•    Gestational diabetes
•    Preeclampsia
•    Sleep apnea
 

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Obesity and Cancer

Cancer Research UK discovered in excess of 33% of all instances of disease were avoidable - somewhere in the range of 123,000. The philanthropy comparatively found that surplus weight currently affected 6.3% of all cancer cases - up from 5.5% in 2011 - while smoking as a root had declined. Cancer Research UK found the nation with the best measure of preventable reasons for cancer was Scotland with 46.5%, trailed by Northern Ireland on 37%, Wales on 37.9%, and England on 36.3%.
 
Over the UK, smoking suffered by far the leading cause of avertible cancer, in spite of the fact that it dropped from 18.4% in 2013 to 14.7%. 

The standard method for distinguishing in the event that somebody is large is by calculating their body mass index (BMI). It preliminaries whether you're a fit load for your stature. A BMI of in excess of 25 methods you're overweight and a BMI of in excess of 30 methods you're named hefty, while there are a few special cases. Cancer Investigation UK discovered overexposure to UV radiation started around 13,600 instances of melanoma skin disease a year - or 3.8% of all disease cases. Other preventable reasons for cancer included drinking liquor and eating too little fiber, it said. Be that as it may, by and large the investigation found the piece of preventable instances of malignant growth had fallen - from 41.3% in 2013 to 33.7%.

•    Endometrial cancer
•    Esophageal adenocarcinoma
•    Gastric cardia cancer
•    Liver cancer
•    Kidney cancer
•    Multiple myeloma
•    Meningioma
•    Pancreatic cancer
•    Colorectal cancer
•    Gallbladder cancer
•    Breast cancer
•    Ovarian cancer
•    Thyroid cancer
•    Teen obesity
•    obesity surgery
•    BMI
 

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Obesity and Nutrition

The body requires a wide range of vitamins and minerals that are essential for both body improvement and prevention of a disease. These nutrients and minerals are known as micronutrients. When a nutritional deficiency occurs the body doesn’t absorb or get necessary amount of a nutrient from the food. Deficiencies can prompt to a variety of health issues like digestion problems, skin disorders, stunted or defective bone development, and even dementia.
On other side our metabolism rate at which our body utilizes our nutrition. While there are numerous factors that impacts our metabolism (hormone levels, enzyme secretion, chronic disease conditions, medications, stress, activity level and sleep patterns). The rate of metabolism directly effects, caloric needs and results in weight loss or weight gain.

•    Fat burning foods
•    Fibre intake
•    Low glycaemic index foods
•    Metabolic disorder
•    Metabolic disease therapy
•    Cardiometabolic disease
 

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Obesity and diabetes

Diabetes is turmoil of carbohydrate metabolism, usually occurring in hereditarily predisposed individuals. Obesity is specially associated with an improved risk of growing Diabetes Mellitus 2 characterized by inadequate secretion or utilization of insulin and ensuing in excessive amounts of glucose in the blood and urine. the great information is that reducing your edge weight, by way of even a small amount, can help upgrade your body's insulin affectability and lessening your risk of growing cardiovascular and metabolic circumstances including type 2 diabetes, heart disease and kinds of most cancers. Obesity meetings awareness on approach and environmental strategies to make fortifying ingesting and active dwelling convenient and lower valued for everyone.

•    Type 1 diabetes mellitus
•    Type 2 diabetes mellitus
 

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Advanced Treatment for Obesity

The primary factor to prevent obesity in children, young people, and adults contributes information on preventing overweight and obesity by modification of lifestyle, focusing on physical activities and well-being, healthy diet along periodical medical examination under masters like dieticians. All kinds of weight problems require changes in physical form deals with weight management in children and adults by regular monitor based on body mass index (BMI). The main treatment for obesity requires physical activities, healthy diet, surgical and non-surgical liposuction. 

•    Morbid Obesity Treatment
•    Combination Therapy for the Treatment Of Obesity
•    Weight loss using Kinesiology
•    Advanced Inch Loss therapy
•    Clinical protocols
•    Ketogenic Diet
•    Protein rich diets
 

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Current Research on Obesity

Around the globe, at scarcest 2.8 million people pass on yearly as it comes to fruition of being overweight or fat, and a surveyed 35.8 million (2.3%) of world DALYs are brought about by overweight or weight. Overweight and bloatedness bring about negative metabolic effects on blood weight, sterol, triglycerides and hypoglycemic administrator obstruction. Perils of coronary heart ailment, cerebrovascular accident and sort 2 diabetes increase predictable with extending weight record (BMI), a level of weight in respect to height. Raised weight list additionally will increase the opportunity of cancer of the breast, colon, prostate, mucous layer, excretory organ and trouble bladder. Death rates increase with extending overweight, as degrees of estimated by weight record. The transcendence of overweight and hugeness were most raised inside the WHO Locales of the Americas (62% for overweight in every sexual orientation, and twenty sixth for weight) and most diminished inside the WHO Locale for South East Asia (14% overweight in males and females and three for corpulence).

•    Drug treatments and devices for Obesity
•    Nutritional Genomics
•    Probiotics for human health
 

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Maternal Obesity

Maternal obesity is the biggest challenge for clinical practice due to high prevalence and several adverse maternal and fetal outcomes. Obesity during pregnancy increases the risk of life-long health problems in children, including obesity, type 2 diabetes, and heart disease. In between 10%–30% of pregnant women are reported to be obese every year internationally. 
•    Obesity
•    Maternal health
•    Diabetes
•    Fetal health
•    Birth outcomes
 

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Microbiota Obesity

Human Microbiota includes bacteria, fungi, archaea, protozoans and viruses that appear to be even more numerous than those in the human genome. Gut microbiota can influence the extraction of energy from food, lipid metabolism, immune response and endocrine functions and its profile has differentiated between obese and lean subjects.
•    Human diabetogenic microbiota
•    Diet-Microbiota Interactions
•    Nutrigenomics and Nutrigenetics
•    Host Metabolism
•    Probiotics
•    Prebiotics

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Morbid Obesity

Morbid Obesity is a severe health condition resulting from an abnormally high body mass index. Obesity and morbid obesity are the result of too much fat stored in your body. Anyone can gain weight and become obese if they eat more calories than their bodies can utilize to covert calories into energy. Other factors, such as stress, anxiety, and insomnia, can lead to weight gain
•    Osteoarthritis
•    Heart disease and blood lipid abnormalities
•    Stroke
•    Type 2 diabetes
•    Sleep apnea (when you periodically stop breathing during sleep)
•    Reproductive problems
•    Gallstones
•    Certain cancers
•    Obesity hypoventilation syndrome
•    Metabolic syndrome
 

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Weight Management

Weight Management is the process of adopting a long-term lifestyle change to keep a healthy body weight based on the age, sex and height of a person. Obesity is a chronic condition in the United States that affects more than one in three adults and about 17% of children and adolescents. Being overweight or obese increases your risk of type 2 diabetes, heart disease, stroke, liver fatty disease, kidney disease, and other health problems.

•    Binge Eating Disorder
•    Weight-loss & Nutrition Myths
•    Helping Your Overweight Child
•    Take Charge of Your Health: A Guide for Teens
•    Food Portions
•    Bariatric Surgery for Severe Obesity
•    Type 2 Diabetes
•    Kidney Disease
•    Fatty Liver (NASH)
•    Heart Disease & Stroke 
•    Sleep Apnea
 

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Diet and Health

The food alternatives we make can have a crucially affect our wellness, Diets concentrated on a heavily clumsy protein stack can be strenuous to save and as often as possible convey their case prosperity hazard. A couple of these risks consolidate stopping up because of a need of dietary fiber, enlarged heart disease possibility (with higher bronzed meat usage), and reduced kidney work for people. Tall Protein Count Calories are kenned to enhearten weight adversity however following to them can be troublesome. Restrict the consumption of sugar and fats, not extra than 30% of the entire calories must come from fat, decide upon unsaturated fat to saturated fat. Avoid taking Trans fats.
The amount of the energy consumed in relevancy to physical activity and also the quality of food are key determinants of nutrition which connects to chronic disease.

•    Heart disease
•    Diabetes
•    Hyperlipidemia
•    Stroke
•    Cancer
•    Osteoporosis and bone fractures
•    Dental disease
 

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Obesity cardiovascular diseases

Obesity is an autonomous hazard factor for cardiovascular Disease, and Cardiovascular Disease dangers have additionally been reported in obese children. Obesity is linked with an increased risk of mortality and horribleness as well as decrease in life expectancy. Medical expenses and health wellbeing health service use associated with obesity have risen and are relied upon to keep on rising.

•    Dyslipidemia
•    Glucose intolerance
•    Coronary heart disease
•    Heart failure
•    Cardiac Stroke
•    Myocardial infarction
•    Hypertension
•    Probiotics for human health
 

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Anti-Obesity Drugs

Anti-obesity drugs or weight hardship drugs are pharmacological experts that reduce or control weight. These drugs alter one of the essential types of the human body, weight control, by modifying either appetite, or maintenance of calories. The most treatment modalities for overweight and robust individuals stay counting calories and physical work out.

•    Anti-obesity agents
•    Obesity
•    Safety
 

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Prevention Control of Obesity

Preventing obesity is very important. Once fat cells structure, they remain in your body until the end of time. Even though you can reduce the size of fat cells, still it’s impossible to get rid of them. Obesity expertise recommend that a key to preventing enormous weight gain is monitoring fat intake instead of counting calories, and therefore the National cholesterol Education Program keeps up that only 30 % of calories ought to be gotten from fat. Only one-third of those calories should be contained in saturated fats (the sensibly fat found in high concentrations in meat, poultry, and dairy farm products).Because the vast majority eat more than they might suspect they do, keeping a point by point nourishment journal is a valuable method to evaluate dietary patterns.

•    Weight loss programs
•    Clinical protocols
•    Ketogenic Diet
•    Protein rich diets
 

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Traditional Chinese Medicine and Acupuncture

Customary Chinese medication is a sort of traditional prescription generally dependent on over 2,500 years of age Chinese therapeutic practice which incorporates different types of herbal therapy, acupuncture (needle therapy), massage therapy, and dietary treatment to prevent medical issues. Acupuncture (needle therapy) includes flimsy needles which are embedded into the body. Needle therapy is normally sheltered when done by appropriately by a prepared specialist utilizing spotless and single-utilized needle strategy.

•    Chinese herbal medicine
•    Tui-na
•    Food therapy
•    Qi-gong
•    Tai-chi

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Liposuction

The time required to do liposuction varies significantly, basing on the size of the area treated, the entirety of fat being expelled, the sort of anesthesia utilized and the liposuction procedures which are chosen. A small area, as such chin or neck can be treated under 30  minutes, while a most wide process might last several hours. During the methodology, a sedated liquid is first infused into the treatment territories before the fat is expelled. This liquid is a blend of vein salt arrangement, lidocaine (a nearby sedative), and epinephrine (a medication that tightens veins). Liposuction works by bringing liquid into the zones where fat should be expelled. At that point, modest cylinders are embedded through scarcely recognizable cuts. The liquid that was embedded enables evacuate to fat all the more adequately when it's sucked out through the channels that were embedded. When the ideal shape is gotten, a compressive piece of clothing is set, this limits recoloring and bolsters in patient solace.

•    Liposuction procedure
•    Liposuction techniques
•    Risks involved in liposuction
•    Cool sculpting technique
•    Zerona method
•    Trusculpt method
 

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Adrenal disorders

Kidney and Heart imbalance 
Kidney and heart imbalance is one of the most widely recognized conflicts of adrenal exhaustion. 
This example ordinarily happens in stressed individuals who utilize the mind in abundance/excess thinking.
The adrenal fatigue symptoms associated are:

•    insomnia
•    heart palpitation
•    anxiety & depression
•    heart conditions
•    emotion instability
•    fibromyalgia and so on
 

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Obesity Psychiatric Disorder

Several investigations have discovered numbers of patients with mental illness are obese compared to the general population. Psychological sickness may expand the danger of weight gain, on other hand obesity may increase an individual's chances to develop a psychiatric disorder. The purpose behind the connection between obesity and psychiatric issues are self portrait/ under confident, the biological disturbances caused by obesity, physical activity and the social shame identified with being overweight. Epidemiological examinations legitimize positive relationship among obesity and state of mind issue.

•    Personality disorder
•    Eating disorder
•    ADHD
•    Alcohol use
•    Mood Disorder
•    Depression
•    Anxiety Disorder
•    Substance use Disorder
 

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Bariatric Surgeries and its Types

Bariatric surgery procedure comprises of methods performed on an individual who experiences obesity, along these lines lessening the hazard related with weight. The fundamental thought behind the medical procedure is confinement and Malabsorption. Surgery procedure confines the measure of food the stomach can hold, accordingly limiting the quantity of calorie consumption. Malabsorption abbreviates the length of small digestive system decreasing the measure of calories and supplements the body can ingest. An obese woman is set three times as liable to be infertile as everyday woman. The obese women have a decrease opportunity of being pregnant as well as have delivered down the shot following in vitro remedy.

•    Gastric by-pass
•    Laparoscopic adjustable gastric banding
•    Sleeve gastrostomy
•    Duodenal switch with biliopancreatic diversion
 

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Non-surgical Treatments for Obesity

The purpose of corpulence treatment is to join achieving and keeping up a strong body. Weight loss treatment, other than weight incident medical procedures fuse dietary changes, physical activity, weight reduction prescription, lead changes, Calorie counting.

•    Dietary Changes
•    Physical Activity
•    Behavior Modification
•    Therapy to Eating Disorders
 

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Novel Concepts in Obesity Drug Development

Obesity is a complex metabolic and behavioural disorder associated with increased health risk, including coronary artery disease, heart failure congestive, and sudden heart death. Effective approaches for obesity prevention and treatment are needed. This unmet need for effective and safe anti-obesity medication at various stages of development resulted in many new therapies. Obesity is one thing
•    Physiology and pathophysiology of adipose tissue
•    Modulators of dietary absorption
•    Animal cell models
•    Human cell models
•    Antiobesity drugs in the pipeline
 

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Obesity Degenerative Diseases

Overweight and obesity are two of the most significant problems in public health. There is a clear link between lifestyle and obesity. This relationship means that unhealthy lifestyles can affect the physiological response of people by means of adipocytokines, pro-inflammatory factors closely linked to chronic degenerative diseases.
•    Metabolic syndrome
•    Malnutrition
•    Gestational diabetes
•    Perinatal nutrition
•    Foetal development
•    Metabolic diseases
•    Central nervous system
•    Energy balance and metabolism
•    Genetic transcription
•    Umbilical cord blood
•    Cardiovascular risk
 

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Pathophysiology of Obesity

Pathophysiology Obesity is caused by an imbalance between energy and caloric intake. This disparity is believed to be under the control of genes and the environment. The discovery of immunological anomalies in obesity linked to the leptin-proopiomelanocortin system and the alpha (TNF-α) elevated tumor necrosis factor brought a new insight to obesity awareness.
•    Genetic basis
•    Environmental and behavioral origins
•    Neurohormones
•    Type 2 diabetes
•    Insulin resistance
 

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Epidemiology of Obesity

Overweight and obesity epidemic poses a major challenge to the prevention and health of chronic diseases throughout the world's life course. Fuelled by economic growth, industrialization, mechanized transport, urbanization, an increasingly sedentary lifestyle, and a dietary transition to processed foods and high-calorie diets over the past 30 years, most countries have witnessed predictions.
•    Prevalence
•    BMI
•    Adiposity
•    Health risk
 

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Etiology of obesity

Obesity is the result of genetic, behavioral, environmental, physiological, social, and cultural factors resulting in energy imbalance and promoting excessive deposition of fat. There has been extensive study of the relative contribution of each of these factors, and although genes play an important role in regulating body weight. Interactions between the genotype and the environment were also involved in the development of obesity.

•    Energy balance
•    Genetics
•    Dietary Intake
•    Physiological functions
•    Leptin
 

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